Post-Doc
May 2016- Term-contract worker (co.co.co) - IRCCS SDN, Naples, Italy and Department of Anatomical, Histological, Forensic and Orthopedic Sciences, Sapienza University, Rome, Italy.
November 2016- Subject Expert in Histology and Embryology- Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy. March 2015-March 2016 PostDoctoral Fellow - Department of Anatomical, Histological, Forensic and Orthopedic Sciences, Sapienza University, Rome, Italy. December 2011-August 2012 Professional activity for:"Applications of cell biology techniques to cultured cardiomyocytes”, in support of the research:"The system of phosphodiesterase as a target pathophysiological cardiac hypertrophy, FIRB, 2010 "- scientific coordinator prof. Andrea M. Isidori, Department of Experimental Medicine, Sapienza University of Rome, Rome. July 2014-January 2015 Visiting graduate student at the University of California, Davis; Department of Pharmacology in Yang Kevin Xiang’s Laboratory. January 2012-December 2014 PhD student in “Health Sciences” at Department of Medicine and Health Sciences, University of Molise (Campobasso) and Visiting graduate student at Department of Anatomical, Histological, Forensic and Orthopedic Sciences, Sapienza University,(Rome) March 2011 Specialistic degree in Applied Cellular Biology, at the University of Rome “La Sapienza”, with a grade of 110/110 and honor. Title of the thesis: “Role of PDE5 in cardiac hypertrophy”. March 2010- December 2011 Training period in the Laboratory of Histology & Medical Embryology, (Prof. Fabio Naro), Department of Anatomical, Histological, Forensic and Orthopedic Sciences, Sapienza University, Faculty of Medicine, Rome. October 2008 First degree in Biology Sciences, at the University of Rome “La Sapienza”. Title of the thesis: “The retinal degeneration in glaucoma shows the molecular aspects in common with Alzheimer's disease”. June 2008-October 2008 Training period in the Laboratory of Physiology (prof.Gianfranco Scarsella), of Department of Genetics and Molecular Biology "Charles Darwin", Sapienza University, Rome. Main research project:
Pubblicazioni:
Assenza MR, Barrios F#, Barbagallo F, Cornacchione M, Campolo F, Vivarelli E, Gianfrilli D, Isidori AM, Lenzi A, Pellegrini M, Naro F. “Critical role of Phosphodiesterase 2A in congenital heart defects.” Cardiovasc Res. 2018 Feb. Fassina L, Cornacchione M, Pellegrini M, Mognaschi ME, Gimmelli R, Isidori AM, Lenzi A, Magenes G, Naro F. “Model of murine ventricular cardiac tissue for in vitro kinematic-dynamic studies of electromagnetic and â-adrenergic stimulation.” J Healthc Eng. 2017 July; 10.1155/2017/4204085 Campolo F, Zevini A, Cardarelli S, Monaco L, Barbagallo F, Pellegrini M, Cornacchione M, Di Grazia A, De Arcangelis V, Gianfrilli D, Giorgi M, Lenzi A, Isidori AM, Naro F. “Identification of murine phosphodiesterase 5A isoforms and their functional characterization in HL-1 cardiac cell line.” J Cell Physiol. 2017 Mar; 10.1002/jcp.25880. Cornacchione M, Pellegrini M, Fassina L, Mognaschi ME, Di Siena S, Gimmelli R, Ambrosino P, Soldovieri MV, Taglialatela M, Gianfrilli D, Isidori AM, Lenzi A, Naro F. “β-adrenergic response is counteracted by extremely-low-frequency pulsed electromagnetic fields in beating cardiomyocytes.” J Mol Cell Cardiol. 2016 Sep;98:146-58. Cornacchione M*,Isidori AM*, Barbagallo F, Di Grazia A, Barrios F, Fassina L, Monaco L, Giannetta E, Gianfrilli D, Garofalo S, Zhang X, Chen X, Xiang YK, Lenzi A, Pellegrini M.# and Naro F.. “Inhibition of type 5 phosphodiesterase counteracts â2-Adrenergic signaling in beating cardiomyocytes.” Cardiovasc Res. 2015 Jun 1;106(3):408-20. *# Equally contributed to the MS; Fassina L, Di Grazia A, Naro F, Aguanno S, Cornacchione M, Cusella De Angelis MG, Sardi F, Magenes G. “Effects of the hydrostatic pressure in in vitro beating cardiac syncytia in terms of kinematics (kinetic energy and beat frequency) and syncytia geometrical functional classification.” Conf Proc IEEE Eng Med Biol Soc. 2013;2013:854-7. Garofalo S, Cornacchione M, Di Costanzo A. “From genetics to genomics of epilepsy”. Neurol Res Int. 2012;2012:876234 |