2020
Therapeutic Use of Pulsed Electromagnetic Field Therapy Reduces Prostate Volume and Lower Urinary Tract Symptoms in Benign Prostatic Hyperplasia. Tenuta M, Tarsitano MG, Mazzotta P, Lucchini L, Sesti F, Fattorini G, Pozza C, Olivieri V, Naro F, Gianfrilli D, Lenzi A, Isidori AM, Pofi R. Andrology. 2020 Feb 23. doi: 10.1111/andr.12775.
Pde2A is Indispensable for Mouse Liver Development and Hematopoiesis. Barbagallo F, Rotilio V, Asswnza MR, Aguano D, Orsini T, Putti S, Isidori AM,
, Lenzi A, Fabio Naro, de Angelis L, Pellegrini M. Int J Mol Sci.2020 Apr 21;21(8). pii: E2902. 2902. doi.org/10.3390/ijms21082902. PubMed PMID: 32326334
Promoting Tissue Repair by Micrograft Stem Cells Delivery.Trovato L, Naro F, D’Aiuto F, Moreno F. Stem Cells Int. 2020. ID 2195318.
Exercise training improves vascular function in patients with Alzheimer’s Disease. Pedrinolla A, Venturelli M, Fonte C, Tamburin S, Di Baldassare A, Naro F, Varalta V, Giuriato G, Ghinassi B, Muti E, Smania N, Schena F. Eur J appl Physiol, 2020.doi:https ://doi. org/10.3233/JAD-132057.
Phosphodiesterase inhibitors: could they be beneficial for the treatment of COVID-19?.Giorgi M, Cardarelli S, Ragusa F, Saliola M, Biagioni S, Poiana G, Naro F, Massimi M. Int J. Mol. Sc., 2020. doi: 10.3390/ijms21155338.
Pde2A is Indispensable for Mouse Liver Development and Hematopoiesis. Barbagallo F, Rotilio V, Asswnza MR, Aguano D, Orsini T, Putti S, Isidori AM,
, Lenzi A, Fabio Naro, de Angelis L, Pellegrini M. Int J Mol Sci.2020 Apr 21;21(8). pii: E2902. 2902. doi.org/10.3390/ijms21082902. PubMed PMID: 32326334
Promoting Tissue Repair by Micrograft Stem Cells Delivery.Trovato L, Naro F, D’Aiuto F, Moreno F. Stem Cells Int. 2020. ID 2195318.
Exercise training improves vascular function in patients with Alzheimer’s Disease. Pedrinolla A, Venturelli M, Fonte C, Tamburin S, Di Baldassare A, Naro F, Varalta V, Giuriato G, Ghinassi B, Muti E, Smania N, Schena F. Eur J appl Physiol, 2020.doi:https ://doi. org/10.3233/JAD-132057.
Phosphodiesterase inhibitors: could they be beneficial for the treatment of COVID-19?.Giorgi M, Cardarelli S, Ragusa F, Saliola M, Biagioni S, Poiana G, Naro F, Massimi M. Int J. Mol. Sc., 2020. doi: 10.3390/ijms21155338.
2019
Atrophy, oxidative switching and ultrastructural defects in skeletal muscle of Ataxia Telangiectasia mouse model. Tassinari V., De Gennaro V., La Sala G., Marazziti D., Bolasco G., Aguanno S., De Angelis L., Naro F, Pellegrini M.J. Cell Sci. 132. pii: jcs223008, 2019. doi: 10.1242/jcs.223008.
Non-Aβ-Dependent factors associated with global cognitive and physical function in Alzheimer’s Disease: a pilot multivariate analysis. Pedrinolla A., Venturelli M., Tamburin S., Fonte C., Stabile A.M., Boscolo Galazzo I., Ghinassi B., Venneri M.A., Pizzini F.B., Muti E., Smania N., Di Baldassarre A., Naro F., Rende M., Schena F. J.Clin.Med. 9;8. pii: E224, 2019. doi: 10.3390/jcm8020224.
Skeletal muscle fiber size and gene expression in the oldest-old with differing degrees of mobility. Naro F., Venturelli M., Monaco L., Toniolo L., Muti E., Milanese C., Zhao J., Richardson R., Schena F., Reggiani C. Frontiers in Physiology-Exercise Physiology accettato 2019. doi: 10.3389/fphys.2019.00313
PDE5 inhibition stimulates Tie2-expressing monocytes and Angiopoietin-1 restoring angiogenic homeostasis in diabetes. Venneri M.A., Barbagallo F.,Fiore F., De Gaetano R., , Giannetta E., Sbardella E., "Pozza C., Campolo F., Naro F., Lenzi A., Isidori A.M. J.C.E.M accettto 2019. doi: 10.1210/jc.2018-02525
Argonaute 2 drives miR-145-5p-dependent gene expression program in breast cancer cells. Bellissimo T, Tito C, Ganci F, Sacconi A, Masciarelli S, Di Martino G, Porta N, Cirenza M, Sorci M, De Angelis L, Rosa P, Calogero A, Fatica A, Petrozza V, Fontemaggi G, Blandino G, Fazi F.Cell Death Dis. 2019. doi: 10.1038/s41419-018-1267-5
Commentaries on Viewpoint: "Muscle memory" not mediated by myonuclear number? Secondary analysis of human detraining data. Venturelli M, Schena F, Naro F, Reggiani C, Pereira Guimarães M, de Almeida Costa Campos Y, Costa Moreira O, Fernandes da Silva S, Silva Marques de Azevedo PH, Dixit A, Srivastav S, Hinkley JM, Seaborne RA, Viggars M, Sharples AP, Mahmassani ZS, Drummond MJ, Gondin J. Appl Physiol (1985). 2019 Dec 1;127(6):1817-1820. doi: 10.1152/japplphysiol.00754.2019.
A Three-Dimensional Culture Model of Reversibly Quiescent Myogenic Cells. Aguanno S, Petrelli C, Di Siena S, De Angelis L, Pellegrini M, Naro F. Stem Cells Int. 2019 Nov 11;2019:7548160. doi: 10.1155/2019/7548160. .
Chronic administration of sildenafil improves endothelial function in spontaneously hypertensive rats by decreasing COX-2 expression and oxidative stress. Teixeira-da-Silva JJ, Nunes-Moreira HS, Silva CO, Lahlou S, Naro F, Xavier FE, Duarte GP. Life Sci. 2019 May 15;225:29-38. doi: 10.1016/j.lfs.2019.03.074
Commentaries on Viewpoint: memory" not mediated by myonuclear number? Secondary analysis of human detraining data. Venturelli M, Schena F, Naro F, Reggiani C, Pereira Guimarães M, de Almeida Costa Campos Y, Costa Moreira O, Fernandes da Silva S, Silva Marques de Azevedo P.H, Dixit A, Srivastav S, Hinkley J.M, Seaborne R.A, Viggars M, Sharples A.P, Mahmassani Z.S, Drummond M.J, Gondin J.J Appl Physiol. 2019. 127:1817-1820. doi:10.1152/japplphysiol.00754. 2019.
Non-Aβ-Dependent factors associated with global cognitive and physical function in Alzheimer’s Disease: a pilot multivariate analysis. Pedrinolla A., Venturelli M., Tamburin S., Fonte C., Stabile A.M., Boscolo Galazzo I., Ghinassi B., Venneri M.A., Pizzini F.B., Muti E., Smania N., Di Baldassarre A., Naro F., Rende M., Schena F. J.Clin.Med. 9;8. pii: E224, 2019. doi: 10.3390/jcm8020224.
Skeletal muscle fiber size and gene expression in the oldest-old with differing degrees of mobility. Naro F., Venturelli M., Monaco L., Toniolo L., Muti E., Milanese C., Zhao J., Richardson R., Schena F., Reggiani C. Frontiers in Physiology-Exercise Physiology accettato 2019. doi: 10.3389/fphys.2019.00313
PDE5 inhibition stimulates Tie2-expressing monocytes and Angiopoietin-1 restoring angiogenic homeostasis in diabetes. Venneri M.A., Barbagallo F.,Fiore F., De Gaetano R., , Giannetta E., Sbardella E., "Pozza C., Campolo F., Naro F., Lenzi A., Isidori A.M. J.C.E.M accettto 2019. doi: 10.1210/jc.2018-02525
Argonaute 2 drives miR-145-5p-dependent gene expression program in breast cancer cells. Bellissimo T, Tito C, Ganci F, Sacconi A, Masciarelli S, Di Martino G, Porta N, Cirenza M, Sorci M, De Angelis L, Rosa P, Calogero A, Fatica A, Petrozza V, Fontemaggi G, Blandino G, Fazi F.Cell Death Dis. 2019. doi: 10.1038/s41419-018-1267-5
Commentaries on Viewpoint: "Muscle memory" not mediated by myonuclear number? Secondary analysis of human detraining data. Venturelli M, Schena F, Naro F, Reggiani C, Pereira Guimarães M, de Almeida Costa Campos Y, Costa Moreira O, Fernandes da Silva S, Silva Marques de Azevedo PH, Dixit A, Srivastav S, Hinkley JM, Seaborne RA, Viggars M, Sharples AP, Mahmassani ZS, Drummond MJ, Gondin J. Appl Physiol (1985). 2019 Dec 1;127(6):1817-1820. doi: 10.1152/japplphysiol.00754.2019.
A Three-Dimensional Culture Model of Reversibly Quiescent Myogenic Cells. Aguanno S, Petrelli C, Di Siena S, De Angelis L, Pellegrini M, Naro F. Stem Cells Int. 2019 Nov 11;2019:7548160. doi: 10.1155/2019/7548160. .
Chronic administration of sildenafil improves endothelial function in spontaneously hypertensive rats by decreasing COX-2 expression and oxidative stress. Teixeira-da-Silva JJ, Nunes-Moreira HS, Silva CO, Lahlou S, Naro F, Xavier FE, Duarte GP. Life Sci. 2019 May 15;225:29-38. doi: 10.1016/j.lfs.2019.03.074
Commentaries on Viewpoint: memory" not mediated by myonuclear number? Secondary analysis of human detraining data. Venturelli M, Schena F, Naro F, Reggiani C, Pereira Guimarães M, de Almeida Costa Campos Y, Costa Moreira O, Fernandes da Silva S, Silva Marques de Azevedo P.H, Dixit A, Srivastav S, Hinkley J.M, Seaborne R.A, Viggars M, Sharples A.P, Mahmassani Z.S, Drummond M.J, Gondin J.J Appl Physiol. 2019. 127:1817-1820. doi:10.1152/japplphysiol.00754. 2019.
2018
The oligomeric assembly of the phosphodiesterase-5 is a mixture of dimers and tetramers: A putative role in the regulation of function. Cardarelli S, Miele A.E, Zamparelli C, Biagioni S, Naro F, Malatesta F, Giorgi M, Saliola M. BBA, 2018. doi.org/10.1016/j.bbagen.2018.07.010
Identification of murine phosphodiesterase 5A isoforms and their functional characterization in HL-1 cardiac cell line. Campolo F1, Zevini A2, Cardarelli S3, Monaco L4, Barbagallo F1, Pellegrini M5, Cornacchione M2, Di Grazia A2, De Arcangelis V2, Gianfrilli D1, Giorgi M3, Lenzi A1, Isidori AM1, Naro F2.. J. Cell Physiol. 2018 Jan;233(1):325-337. doi: 10.1002/jcp.25880.
The circadian rhythm of glucocorticoid administration regulates metabolism and the innate immunity of adrenally insufficient patients. Venneri MA1, Hasenmajer V1, Fiore D1, Sbardella E1, Pofi R1,2, Graziadio C1, Gianfrilli D1, Pivonello C3, Negri M3, Naro F4, Grossman AB2,5, Lenzi A1, Pivonello R3, Isidori AM1. 2018 Aug 1;103(8):2998-3009. doi: 10.1210/jc.2018-00346
Chronic phosphodiesterase type 5 inhibition has beneficial effects on subcutaneous adipose tissue plasticity in type 2 diabetic mice. Fiore D1, Gianfrilli D1, Cardarelli S1, Naro F2, Lenzi A1, Isidori AM1, Venneri MA1.2018 Aug 1;103(8):2998-3009. doi: 10.1210/jc.2018-00346.
J. Cell Physiol 233:8411-8417, 2018.
Ergotropic Effect in Cardiac Tissue After Electromagnetic and β-Adrenergic Stimulus. Fassina L., Cornacchione M., Mognaschi M.E., Magenes G., Naro F. doi: 10.1007/978-3-319-96649-6_4 75-85, 2018
Critical role of phosphodiesterase 2A in mouse congenital heart defects. Assenza MR1, Barbagallo F2, Barrios F1, Cornacchione M3, Campolo F2, Vivarelli E1, Gianfrilli D2, Auletta L3, Soricelli A3,4, Isidori AM2, Lenzi A2, Pellegrini M2,5, Naro F1.2018 May 1;114(6):830-845. doi: 10.1093/cvr/cvy030
Identification of murine phosphodiesterase 5A isoforms and their functional characterization in HL-1 cardiac cell line. Campolo F1, Zevini A2, Cardarelli S3, Monaco L4, Barbagallo F1, Pellegrini M5, Cornacchione M2, Di Grazia A2, De Arcangelis V2, Gianfrilli D1, Giorgi M3, Lenzi A1, Isidori AM1, Naro F2.. J. Cell Physiol. 2018 Jan;233(1):325-337. doi: 10.1002/jcp.25880.
The circadian rhythm of glucocorticoid administration regulates metabolism and the innate immunity of adrenally insufficient patients. Venneri MA1, Hasenmajer V1, Fiore D1, Sbardella E1, Pofi R1,2, Graziadio C1, Gianfrilli D1, Pivonello C3, Negri M3, Naro F4, Grossman AB2,5, Lenzi A1, Pivonello R3, Isidori AM1. 2018 Aug 1;103(8):2998-3009. doi: 10.1210/jc.2018-00346
Chronic phosphodiesterase type 5 inhibition has beneficial effects on subcutaneous adipose tissue plasticity in type 2 diabetic mice. Fiore D1, Gianfrilli D1, Cardarelli S1, Naro F2, Lenzi A1, Isidori AM1, Venneri MA1.2018 Aug 1;103(8):2998-3009. doi: 10.1210/jc.2018-00346.
J. Cell Physiol 233:8411-8417, 2018.
Ergotropic Effect in Cardiac Tissue After Electromagnetic and β-Adrenergic Stimulus. Fassina L., Cornacchione M., Mognaschi M.E., Magenes G., Naro F. doi: 10.1007/978-3-319-96649-6_4 75-85, 2018
Critical role of phosphodiesterase 2A in mouse congenital heart defects. Assenza MR1, Barbagallo F2, Barrios F1, Cornacchione M3, Campolo F2, Vivarelli E1, Gianfrilli D2, Auletta L3, Soricelli A3,4, Isidori AM2, Lenzi A2, Pellegrini M2,5, Naro F1.2018 May 1;114(6):830-845. doi: 10.1093/cvr/cvy030
2017
Model of Murine Ventricular Cardiac Tissue for In Vitro Kinematic-Dynamic Studies of Electromagnetic and Adrenergic Stimulation. Fassina L, Cornacchione M, Pellegrini M, Mognaschi ME, Gimmelli R, Isidori AM, Lenzi A, Magenes G, Naro F. J Healthc Eng. 2017;2017:4204085. doi: 10.1155/2017/4204085. Epub 2017 Aug 8. PMID: 29065600
A Comparison of Lysosomal Enzymes Expression Levels in Peripheral Liquid Biopsy of MILD-, Severe-Alzheimer’s Disease and MCI patients: Implication for Regenerative Medicine Approaches. Morena F., Argentati C., Trotta R., Crispoltoni L., Stabile A., Pistilli A., Di Baldassarre A., Calafiore R., Montanucci P., Basta G., Pedrinolla A., Smania N., Venturelli M., Schena F., Naro F., Emiliani C., Rende M., Martino S. Int. J. of Mol. Sc. 18: E1806, 2017.
Use of the KlADH3 promoter for the quantitative production of the murine PDE5A isoforms in the yeast Kluyveromyces lactis. Cardarelli S., Giorgi M., Naro F., Malatesta F., Biagioni S., Saliola M. Microbial Cell Factories. 16:159 2017.
Phosphodiesterase-5 inhibition preserves renal hemodynamics and function in mice with diabetic kidney disease by modulating miR-22 and BMP7. Pofi R., Fiore D., De Gaetano R., Panio G., Gianfrilli G., Pozza C., Barbagallo F., Xiang Y., Giannakakis K., Morano S., Lenzi A., Naro F., Isidori A.M., Venneri M. Scientific Reports 7:44584, 2017 PMID:28294194
Identification of murine Phosphodiesterase 5A isoforms and their functional characterization in HL-1 cardiac cell line. Campolo F., Zevini A., Cardarelli S., Monaco L., Barbagallo F., Pellegrini M., Cornacchione M., Di Grazia A., De Arcangelis V., Gianfrilli D., Giorgi M., Lenzi A., Isidori A.M., Naro F. J Cell Physiol. 2017 Mar 1. PMID: 28247930
Effect of once-daily, modified-release hydrocortisone versus standard glucocorticoid therapy on metabolism and innate immunity in patients with adrenal insufficiency (DREAM): a single-blind, randomised controlled trial .Isidori AM, Venneri MA, Graziadio C, Simeoli C, Fiore D, Hasenmajer V, Sbardella E, Gianfrilli D, Pozza C, Pasqualetti P, Morrone S, Santoni A, Naro F, Colao A, Pivonello R, Lenzi A.
Lancet Diabetes Endocrinol. 2018 Mar;6(3):173-185. doi: 10.1016/S2213-8587(17)30398-4. Epub 2017 Dec 8.
Age-associated ALU element instability in white blood cells is linked to lower survival in elderly adults: a preliminary cohort study. Garrett R., Venturelli M., Gross C., Tarperi C., Schena F., Reggiani C., Naro F., Pedrinolla A., Monaco L., Richardons R., Donato A. Plos One, 12: e0169628, 2017 PMID: 28060910
The cardioprotective effect of sildenafil is mediated by the activation of malate dehydrogenase and an increase in the malate-aspartate shuttle in cardiomyocytes. Gevi F., Campolo F., Naro F., Zolla L. Biochem. Pharmacol. 127: 60-70, 2017. PMID: 28017777
Thymic Epithelial Tumors phenotype relies on miR-145-5p epigenetic regulation. Bellissimo T, Ganci F, Gallo E, Sacconi A, Tito C, De Angelis L, Pulito C, Masciarelli S, Diso D, Anile M, Petrozza V , Giangaspero F, Pescarmona E, Facciolo F, Venuta F, Marino M, Blandino G, Faz F. Mol Cancer. 2017. doi: 10.1186/s12943-017-0655-2
A Comparison of Lysosomal Enzymes Expression Levels in Peripheral Liquid Biopsy of MILD-, Severe-Alzheimer’s Disease and MCI patients: Implication for Regenerative Medicine Approaches. Morena F., Argentati C., Trotta R., Crispoltoni L., Stabile A., Pistilli A., Di Baldassarre A., Calafiore R., Montanucci P., Basta G., Pedrinolla A., Smania N., Venturelli M., Schena F., Naro F., Emiliani C., Rende M., Martino S. Int. J. of Mol. Sc. 18: E1806, 2017.
Use of the KlADH3 promoter for the quantitative production of the murine PDE5A isoforms in the yeast Kluyveromyces lactis. Cardarelli S., Giorgi M., Naro F., Malatesta F., Biagioni S., Saliola M. Microbial Cell Factories. 16:159 2017.
Phosphodiesterase-5 inhibition preserves renal hemodynamics and function in mice with diabetic kidney disease by modulating miR-22 and BMP7. Pofi R., Fiore D., De Gaetano R., Panio G., Gianfrilli G., Pozza C., Barbagallo F., Xiang Y., Giannakakis K., Morano S., Lenzi A., Naro F., Isidori A.M., Venneri M. Scientific Reports 7:44584, 2017 PMID:28294194
Identification of murine Phosphodiesterase 5A isoforms and their functional characterization in HL-1 cardiac cell line. Campolo F., Zevini A., Cardarelli S., Monaco L., Barbagallo F., Pellegrini M., Cornacchione M., Di Grazia A., De Arcangelis V., Gianfrilli D., Giorgi M., Lenzi A., Isidori A.M., Naro F. J Cell Physiol. 2017 Mar 1. PMID: 28247930
Effect of once-daily, modified-release hydrocortisone versus standard glucocorticoid therapy on metabolism and innate immunity in patients with adrenal insufficiency (DREAM): a single-blind, randomised controlled trial .Isidori AM, Venneri MA, Graziadio C, Simeoli C, Fiore D, Hasenmajer V, Sbardella E, Gianfrilli D, Pozza C, Pasqualetti P, Morrone S, Santoni A, Naro F, Colao A, Pivonello R, Lenzi A.
Lancet Diabetes Endocrinol. 2018 Mar;6(3):173-185. doi: 10.1016/S2213-8587(17)30398-4. Epub 2017 Dec 8.
Age-associated ALU element instability in white blood cells is linked to lower survival in elderly adults: a preliminary cohort study. Garrett R., Venturelli M., Gross C., Tarperi C., Schena F., Reggiani C., Naro F., Pedrinolla A., Monaco L., Richardons R., Donato A. Plos One, 12: e0169628, 2017 PMID: 28060910
The cardioprotective effect of sildenafil is mediated by the activation of malate dehydrogenase and an increase in the malate-aspartate shuttle in cardiomyocytes. Gevi F., Campolo F., Naro F., Zolla L. Biochem. Pharmacol. 127: 60-70, 2017. PMID: 28017777
Thymic Epithelial Tumors phenotype relies on miR-145-5p epigenetic regulation. Bellissimo T, Ganci F, Gallo E, Sacconi A, Tito C, De Angelis L, Pulito C, Masciarelli S, Diso D, Anile M, Petrozza V , Giangaspero F, Pescarmona E, Facciolo F, Venuta F, Marino M, Blandino G, Faz F. Mol Cancer. 2017. doi: 10.1186/s12943-017-0655-2
2016
Genetically Encoded Biosensors Reveal PKA Hyperphosphorylation on the Myofilaments in Rabbit Heart Failure. Barbagallo F, Xu B, Reddy GR, West T, Wang Q, Fu Q, Li M, Shi Q, Ginsburg KS, Ferrier W, Isidori AM, Naro F, Patel HH, Bossuyt J, Bers D, Xiang YK. Circ Res. 2016 Sep 30;119(8):931-43. doi: 10.1161/CIRCRESAHA.116.308964. Epub 2016 Aug 30. PMID: 27576469
Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury. Di Siena S, Gimmelli R, Nori SL, Barbagallo F, Campolo F, Dolci S, Rossi P, Venneri MA, Giannetta E, Gianfrilli D, Feigenbaum L, Lenzi A, Naro F, Cianflone E, Mancuso T, Torella D, Isidori AM, Pellegrini M. Cell Death Dis. 2016 Jul 28;7(7):e2317. doi: 10.1038/cddis.2016.205. PMID: 27468693
β-Adrenergic response is counteracted by extremely-low-frequency pulsed electromagnetic fields in beating cardiomyocytes. Cornacchione M, Pellegrini M, Fassina L, Mognaschi ME, Di Siena S, Gimmelli R, Ambrosino P, Soldovieri MV, Taglialatela M, Gianfrilli D, Isidori AM, Lenzi A, Naro F. J Mol Cell Cardiol. 2016 Sep;98:146-58. doi: 10.1016/j.yjmcc.2016.07.004. Epub 2016 Jul 11. PMID: 27418252
A surge of late-occurring meiotic double-strand breaks rescues synapsis abnormalities in spermatocytes of mice with hypomorphic expression of SPO11. Faieta M, Di Cecca S, de Rooij DG, Luchetti A, Murdocca M, Di Giacomo M, Di Siena S, Pellegrini M, Rossi P, Barchi M. Chromosoma. 2016 Jun;125(2):189-203. doi: 10.1007/s00412-015-0544-7. Epub 2015 Oct 6. PMID: 26440409
PDE5 Inhibition Ameliorates Visceral Adiposity Targeting the miR-22/SIRT1 Pathway: Evidence From the CECSID Trial. Fiore D, Gianfrilli D, Giannetta E, Galea N, Panio G, di Dato C, Pofi R, Pozza C, Sbardella E, Carbone I, Naro F, Lenzi A, Venneri MA, Isidori AM. J Clin Endocrinol Metab. 2016 Apr;101(4):1525-34. doi: 10.1210/jc.2015-4252. Epub 2016 Mar 10. PMID: 26964730
Expression and Function of Phosphodiesterase Type 5 in Human Breast Cancer Cell Lines and Tissues: Implications for Targeted Therapy. Catalano S, Campana A, Giordano C, Győrffy B, Tarallo R, Rinaldi A, Bruno G, Ferraro A, Romeo F, Lanzino M, Naro F, Bonofiglio D, Andò S, Barone I. Clin Cancer Res. 2016 May 1;22(9):2271-82. doi: 10.1158/1078-0432.CCR-15-1900. Epub 2015 Dec 14. PMID: 26667489
Pathways Implicated in Tadalafil Amelioration of Duchenne Muscular Dystrophy. De Arcangelis V, Strimpakos G, Gabanella F, Corbi N, Luvisetto S, Magrelli A, Onori A, Passananti C, Pisani C, Rome S, Severini C, Naro F, Mattei E, Di Certo MG, Monaco L. J Cell Physiol. 2016 Jan;231(1):224-32. doi: 10.1002/jcp.25075. PMID: 26097015
Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury. Di Siena S, Gimmelli R, Nori SL, Barbagallo F, Campolo F, Dolci S, Rossi P, Venneri MA, Giannetta E, Gianfrilli D, Feigenbaum L, Lenzi A, Naro F, Cianflone E, Mancuso T, Torella D, Isidori AM, Pellegrini M. Cell Death Dis. 2016 Jul 28;7(7):e2317. doi: 10.1038/cddis.2016.205. PMID: 27468693
β-Adrenergic response is counteracted by extremely-low-frequency pulsed electromagnetic fields in beating cardiomyocytes. Cornacchione M, Pellegrini M, Fassina L, Mognaschi ME, Di Siena S, Gimmelli R, Ambrosino P, Soldovieri MV, Taglialatela M, Gianfrilli D, Isidori AM, Lenzi A, Naro F. J Mol Cell Cardiol. 2016 Sep;98:146-58. doi: 10.1016/j.yjmcc.2016.07.004. Epub 2016 Jul 11. PMID: 27418252
A surge of late-occurring meiotic double-strand breaks rescues synapsis abnormalities in spermatocytes of mice with hypomorphic expression of SPO11. Faieta M, Di Cecca S, de Rooij DG, Luchetti A, Murdocca M, Di Giacomo M, Di Siena S, Pellegrini M, Rossi P, Barchi M. Chromosoma. 2016 Jun;125(2):189-203. doi: 10.1007/s00412-015-0544-7. Epub 2015 Oct 6. PMID: 26440409
PDE5 Inhibition Ameliorates Visceral Adiposity Targeting the miR-22/SIRT1 Pathway: Evidence From the CECSID Trial. Fiore D, Gianfrilli D, Giannetta E, Galea N, Panio G, di Dato C, Pofi R, Pozza C, Sbardella E, Carbone I, Naro F, Lenzi A, Venneri MA, Isidori AM. J Clin Endocrinol Metab. 2016 Apr;101(4):1525-34. doi: 10.1210/jc.2015-4252. Epub 2016 Mar 10. PMID: 26964730
Expression and Function of Phosphodiesterase Type 5 in Human Breast Cancer Cell Lines and Tissues: Implications for Targeted Therapy. Catalano S, Campana A, Giordano C, Győrffy B, Tarallo R, Rinaldi A, Bruno G, Ferraro A, Romeo F, Lanzino M, Naro F, Bonofiglio D, Andò S, Barone I. Clin Cancer Res. 2016 May 1;22(9):2271-82. doi: 10.1158/1078-0432.CCR-15-1900. Epub 2015 Dec 14. PMID: 26667489
Pathways Implicated in Tadalafil Amelioration of Duchenne Muscular Dystrophy. De Arcangelis V, Strimpakos G, Gabanella F, Corbi N, Luvisetto S, Magrelli A, Onori A, Passananti C, Pisani C, Rome S, Severini C, Naro F, Mattei E, Di Certo MG, Monaco L. J Cell Physiol. 2016 Jan;231(1):224-32. doi: 10.1002/jcp.25075. PMID: 26097015
2015
In vivo and in vitro evidence that intrinsic upper- and lower-limb skeletal muscle function is unaffected by ageing and disuse in oldest-old humans. Venturelli M, Saggin P, Muti E, Naro F, Cancellara L, Toniolo L, Tarperi C, Calabria E, Richardson RS, Reggiani C, Schena F. Acta Physiol (Oxf). 2015 Sep;215(1):58-71. doi: 10.1111/apha.12524. Epub 2015 May 28. PMID: 25965867
Chronic Inhibition of PDE5 Limits Pro-Inflammatory Monocyte-Macrophage Polarization in Streptozotocin-Induced Diabetic Mice. Venneri MA, Giannetta E, Panio G, De Gaetano R, Gianfrilli D, Pofi R, Masciarelli S, Fazi F, Pellegrini M, Lenzi A, Naro F, Isidori AM. PLoS One. 2015 May 11;10(5):e0126580. doi: 10.1371/journal.pone.0126580. eCollection 2015. PMID: 25961566
Inhibition of type 5 phosphodiesterase counteracts β2-adrenergic signalling in beating cardiomyocytes. Isidori AM, Cornacchione M, Barbagallo F, Di Grazia A, Barrios F, Fassina L, Monaco L, Giannetta E, Gianfrilli D, Garofalo S, Zhang X, Chen X, Xiang YK, Lenzi A, Pellegrini M, Naro F. Cardiovasc Res. 2015 Jun 1;106(3):408-20. doi: 10.1093/cvr/cvv123. Epub 2015 Apr 7. PMID: 25852085
Akt-mediated phosphorylation controls the activity of the Y-box protein MSY3 in skeletal muscle. De Angelis L, Balasubramanian S, Berghella L.
Skelet Muscle. 2015 May 29;5:18. doi: 10.1186/s13395-015-0043-9. eCollection 2015. PMID: 26146542
Modulation of the cardiomyocyte contraction inside a hydrostatic pressure bioreactor: in vitro verification of the Frank-Starling law. Fassina L, Magenes G, Gimmelli R, Naro F. Biomed Res Int. 2015;2015:542105. doi: 10.1155/2015/542105. Epub 2015 Jan 15. PMID: 25667923
Akt-mediated phosphorylation controls the activity of the Y-box protein MSY3 in skeletal muscle. De Angelis L, Balasubramanian S, Berghella L. Skelet Muscle. 2015. doi: 10.1186/s13395-015-0043-9. eCollection 2015
Chronic Inhibition of PDE5 Limits Pro-Inflammatory Monocyte-Macrophage Polarization in Streptozotocin-Induced Diabetic Mice. Venneri MA, Giannetta E, Panio G, De Gaetano R, Gianfrilli D, Pofi R, Masciarelli S, Fazi F, Pellegrini M, Lenzi A, Naro F, Isidori AM. PLoS One. 2015 May 11;10(5):e0126580. doi: 10.1371/journal.pone.0126580. eCollection 2015. PMID: 25961566
Inhibition of type 5 phosphodiesterase counteracts β2-adrenergic signalling in beating cardiomyocytes. Isidori AM, Cornacchione M, Barbagallo F, Di Grazia A, Barrios F, Fassina L, Monaco L, Giannetta E, Gianfrilli D, Garofalo S, Zhang X, Chen X, Xiang YK, Lenzi A, Pellegrini M, Naro F. Cardiovasc Res. 2015 Jun 1;106(3):408-20. doi: 10.1093/cvr/cvv123. Epub 2015 Apr 7. PMID: 25852085
Akt-mediated phosphorylation controls the activity of the Y-box protein MSY3 in skeletal muscle. De Angelis L, Balasubramanian S, Berghella L.
Skelet Muscle. 2015 May 29;5:18. doi: 10.1186/s13395-015-0043-9. eCollection 2015. PMID: 26146542
Modulation of the cardiomyocyte contraction inside a hydrostatic pressure bioreactor: in vitro verification of the Frank-Starling law. Fassina L, Magenes G, Gimmelli R, Naro F. Biomed Res Int. 2015;2015:542105. doi: 10.1155/2015/542105. Epub 2015 Jan 15. PMID: 25667923
Akt-mediated phosphorylation controls the activity of the Y-box protein MSY3 in skeletal muscle. De Angelis L, Balasubramanian S, Berghella L. Skelet Muscle. 2015. doi: 10.1186/s13395-015-0043-9. eCollection 2015
2014
Field models and numerical dosimetry inside an extremely-low-frequency electromagnetic bioreactor: the theoretical link between the electromagnetically induced mechanical forces and the biological mechanisms of the cell tensegrity. Mognaschi ME, Di Barba P, Magenes G, Lenzi A, Naro F, Fassina L. Springerplus. 2014 Aug 27;3:473. doi: 10.1186/2193-1801-3-473. eCollection 2014. PMID: 25202652
Supplementation of anti-oxidants in leucofiltered erythrocyte concentrates: assessment of morphological changes through scanning electron microscopy. Pallotta V, Naro F, Gevi F, D'Alessandro A, Zolla L. Blood Transfus. 2014 Jul;12(3):421-4. doi: 10.2450/2014.0272-13. Epub 2014 Jun 5. No abstract available. PMID: 25074789
Cellular aging of skeletal muscle: telomeric and free radical evidence that physical inactivity is responsible and not age. Venturelli M, Morgan GR, Donato AJ, Reese V, Bottura R, Tarperi C, Milanese C, Schena F, Reggiani C, Naro F, Cawthon RM, Richardson RS. Clin Sci (Lond). 2014 Sep;127(6):415-21. doi: 10.1042/CS20140051. PMID: 24708050
Supplementation of anti-oxidants in leucofiltered erythrocyte concentrates: assessment of morphological changes through scanning electron microscopy. Pallotta V, Naro F, Gevi F, D'Alessandro A, Zolla L. Blood Transfus. 2014 Jul;12(3):421-4. doi: 10.2450/2014.0272-13. Epub 2014 Jun 5. No abstract available. PMID: 25074789
Cellular aging of skeletal muscle: telomeric and free radical evidence that physical inactivity is responsible and not age. Venturelli M, Morgan GR, Donato AJ, Reese V, Bottura R, Tarperi C, Milanese C, Schena F, Reggiani C, Naro F, Cawthon RM, Richardson RS. Clin Sci (Lond). 2014 Sep;127(6):415-21. doi: 10.1042/CS20140051. PMID: 24708050
2013
Effects of the hydrostatic pressure in in vitro beating cardiac syncytia in terms of kinematics (kinetic energy and beat frequency) and syncytia geometrical-functional classification. Fassina L, Di Grazia A, Naro F, Aguanno S, Cornacchione M, Cusella De Angelis MG, Sardi F, Magenes G. Conf Proc IEEE Eng Med Biol Soc. 2013;2013:854-7. doi: 10.1109/EMBC.2013.6609635. PMID: 24109822
Phospholipase D regulates the size of skeletal muscle cells through the activation of mTOR signaling. Jaafar R, De Larichaudy J, Chanon S, Euthine V, Durand C, Naro F, Bertolino P, Vidal H, Lefai E, Némoz G. Cell Commun Signal. 2013 Aug 2;11:55. doi: 10.1186/1478-811X-11-55. PMID: 23915343
Sources for skeletal muscle repair: from satellite cells to reprogramming. Sirabella D, De Angelis L, Berghella L. J Cachexia Sarcopenia Muscle. 2013 Jun;4(2):125-36. doi: 10.1007/s13539-012-0098-y. Epub 2013 Jan 12. PMID: 23314905
UV and genotoxic stress induce ATR relocalization in mouse spermatocytes. Di Siena S, Campolo F, Rossi P, Jannini EA, Dolci S, Pellegrini M. Int J Dev Biol. 2013;57(2-4):281-7. doi: 10.1387/ijdb.130039sd. PMID: 23784839
Phospholipase D regulates the size of skeletal muscle cells through the activation of mTOR signaling. Jaafar R, De Larichaudy J, Chanon S, Euthine V, Durand C, Naro F, Bertolino P, Vidal H, Lefai E, Némoz G. Cell Commun Signal. 2013 Aug 2;11:55. doi: 10.1186/1478-811X-11-55. PMID: 23915343
Sources for skeletal muscle repair: from satellite cells to reprogramming. Sirabella D, De Angelis L, Berghella L. J Cachexia Sarcopenia Muscle. 2013 Jun;4(2):125-36. doi: 10.1007/s13539-012-0098-y. Epub 2013 Jan 12. PMID: 23314905
UV and genotoxic stress induce ATR relocalization in mouse spermatocytes. Di Siena S, Campolo F, Rossi P, Jannini EA, Dolci S, Pellegrini M. Int J Dev Biol. 2013;57(2-4):281-7. doi: 10.1387/ijdb.130039sd. PMID: 23784839
2012
Inflammation in muscular dystrophy and the beneficial effects of non-steroidal anti-inflammatory drugs. Serra F, Quarta M, Canato M, Toniolo L, De Arcangelis V, Trotta A, Spath L, Monaco L, Reggiani C, Naro F. Muscle Nerve. 2012 Nov;46(5):773-84. doi: 10.1002/mus.23432. Epub 2012 Jul 27. PMID: 22847332
Chronic Inhibition of cGMP phosphodiesterase 5A improves diabetic cardiomyopathy: a randomized, controlled clinical trial using magnetic resonance imaging with myocardial tagging. Giannetta E, Isidori AM, Galea N, Carbone I, Mandosi E, Vizza CD, Naro F, Morano S, Fedele F, Lenzi A. Circulation. 2012 May 15;125(19):2323-33. doi: 10.1161/CIRCULATIONAHA.111.063412. Epub 2012 Apr 11. PMID: 22496161
TNF-α- and tumor-induced skeletal muscle atrophy involves sphingolipid metabolism. De Larichaudy J, Zufferli A, Serra F, Isidori AM, Naro F, Dessalle K, Desgeorges M, Piraud M, Cheillan D, Vidal H, Lefai E, Némoz G. Skelet Muscle. 2012 Jan 18;2(1):2. doi: 10.1186/2044-5040-2-2. PMID: 22257771
Chronic Inhibition of cGMP phosphodiesterase 5A improves diabetic cardiomyopathy: a randomized, controlled clinical trial using magnetic resonance imaging with myocardial tagging. Giannetta E, Isidori AM, Galea N, Carbone I, Mandosi E, Vizza CD, Naro F, Morano S, Fedele F, Lenzi A. Circulation. 2012 May 15;125(19):2323-33. doi: 10.1161/CIRCULATIONAHA.111.063412. Epub 2012 Apr 11. PMID: 22496161
TNF-α- and tumor-induced skeletal muscle atrophy involves sphingolipid metabolism. De Larichaudy J, Zufferli A, Serra F, Isidori AM, Naro F, Dessalle K, Desgeorges M, Piraud M, Cheillan D, Vidal H, Lefai E, Némoz G. Skelet Muscle. 2012 Jan 18;2(1):2. doi: 10.1186/2044-5040-2-2. PMID: 22257771
2011
Video evaluation of the kinematics and dynamics of the beating cardiac syncytium: an alternative to the Langendorff method. Fassina L, Di Grazia A, Naro F, Monaco L, De Angelis MG, Magenes G. Int J Artif Organs. 2011 Jul;34(7):546-58. doi: 10.5301/IJAO.2011.8510. PMID: 21786253
Phospholipase D regulates myogenic differentiation through the activation of both mTORC1 and mTORC2 complexes. Jaafar R, Zeiller C, Pirola L, Di Grazia A, Naro F, Vidal H, Lefai E, Némoz G. J Biol Chem. 2011 Jun 24;286(25):22609-21. doi: 10.1074/jbc.M110.203885. Epub 2011 Apr 27. PMID: 21525000
Phospholipase D regulates myogenic differentiation through the activation of both mTORC1 and mTORC2 complexes. Jaafar R, Zeiller C, Pirola L, Di Grazia A, Naro F, Vidal H, Lefai E, Némoz G. J Biol Chem. 2011 Jun 24;286(25):22609-21. doi: 10.1074/jbc.M110.203885. Epub 2011 Apr 27. PMID: 21525000
2010
[Radon risk and prevention]. Caciari T, Tomei F, Fiaschetti M, Giubilati R, Ponticiello BG, De Sio S, Naro F, Tomei G, Sancini A. G Ital Med Lav Ergon. 2010 Oct-Dec;32(4 Suppl):240-4. Italian. PMID: 21438271
β1-syntrophin modulation by miR-222 in mdx mice. De Arcangelis V, Serra F, Cogoni C, Vivarelli E, Monaco L, Naro F. PLoS One. 2010 Aug 10;5(8). pii: e12098. doi: 10.1371/journal.pone.0012098. PMID: 20856896
Explant-derived human dental pulp stem cells enhance differentiation and proliferation potentials. Spath L, Rotilio V, Alessandrini M, Gambara G, De Angelis L, Mancini M, Mitsiadis TA, Vivarelli E, Naro F, Filippini A, Papaccio G. J Cell Mol Med. 2010 Jun;14(6B):1635-44. doi: 10.1111/j.1582-4934.2009.00848.x. Epub 2009 Jul 7. PMID: 19602052
β1-syntrophin modulation by miR-222 in mdx mice. De Arcangelis V, Serra F, Cogoni C, Vivarelli E, Monaco L, Naro F. PLoS One. 2010 Aug 10;5(8). pii: e12098. doi: 10.1371/journal.pone.0012098. PMID: 20856896
Explant-derived human dental pulp stem cells enhance differentiation and proliferation potentials. Spath L, Rotilio V, Alessandrini M, Gambara G, De Angelis L, Mancini M, Mitsiadis TA, Vivarelli E, Naro F, Filippini A, Papaccio G. J Cell Mol Med. 2010 Jun;14(6B):1635-44. doi: 10.1111/j.1582-4934.2009.00848.x. Epub 2009 Jul 7. PMID: 19602052